Psycho- physiologic Effects of High Intensity Interval Trainings in Aged Ovariectomized Rats: a Pilot Study

Document Type : Original Article

Authors

Department of Exercise Physiology, Shiraz University, Shiraz, Iran

Abstract

Introduction: Menopause is one of the most important events in a woman's life that affects their physical and mental aspects. The aim of this study was to investigate the physiological and psychological effects of high intensity interval trainings (HIIT) in aged ovariectomized rats. Methods: In this experimental study, 12 aged ovariectomized rats were randomly divided into two groups of six including HIIT and control. HIIT group received training for eight weeks, three sessions per week, and 9 interval (each interval 1 minute) with intensity of 90- 95% VO2max and one minute running between each interval with intensity of 50% VO2max. 24 hours after the last training session, weights, visceral fat mass, anxiety-like behaviors and depression were measured. To statistical analysis of data Shapiro- Wilk test, paired sample t- test and independent sample t-test were used (p≤ 0.05). Results: Body weight (p = 0.002), visceral fat mass (p = 0.001) and duration of immobilization (p = 0.001) in HIIT training group were significantly lower than control group and percentage of elapsed time in the open arm (p = 0.003), the percentage of number of entrance to open arms (p = 0.03) and aerobic power (p = 0.001) in the HIIT group was significantly higher than the control group. Conclusion: It seems that HIIT have positive effects on the physiological and psychological factors of aged ovariectomized rats.

Keywords

References

1.   Dalal PK, Agarwal M. Postmenopausal syndrome. Indian journal of psychiatry. 2015;57(Suppl 2):S222-S32.
2.   Li R-X, Ma M, Xiao X-R, Xu Y, Chen X-Y, Li B. Perimenopausal syndrome and mood disorders in perimenopause: prevalence, severity, relationships, and risk factors. Medicine. 2016;95(32):e4466-e.
3.   Kozakowski J, Gietka-Czernel M, Leszczyńska D, Majos A. Obesity in menopause - our negligence or an unfortunate inevitability? Przeglad menopauzalny = Menopause review. 2017;16(2):61-5.
4.   Karvonen-Gutierrez C, Kim C. Association of Mid-Life Changes in Body Size, Body Composition and Obesity Status with the Menopausal Transition. Healthcare (Basel, Switzerland). 2016;4(3):42.
5.   Friedenreich CM, Ruan Y, Duha A, Courneya KS. Exercise Dose Effects on Body Fat 12 Months after an Exercise Intervention: Follow-up from a Randomized Controlled Trial. Journal of obesity. 2019;2019:3916416-.
6.   Khosravi N, Eskandari Z, Farajivafa V, Hanson E, Agha-alinejad H, Abdollah-pour A, et al. Effect of 6 months of aerobic training on adipokines as breast cancer risk factors in postmenopausal women: A randomized controlled trial. Journal of Cancer Research and Therapeutics. 2018;14(6):1336-40.
7.   Gentry AL, Erickson KI, Sereika SM, Casillo FE, Crisafio ME, Donahue PT, et al. Protocol for Exercise Program in Cancer and Cognition (EPICC): A randomized controlled trial of the effects of aerobic exercise on cognitive function in postmenopausal women with breast cancer receiving aromatase inhibitor therapy. Contemporary clinical trials. 2018;67:109-15.
8.   Abedi P, Nikkhah P, Najar S. Effect of pedometer-based walking on depression, anxiety and insomnia among postmenopausal women. Climacteric. 2015;18(6):841-5.
9.   Courneya KS, McNeil J, O'Reilly R, Morielli AR, Friedenreich CM. Dose-response effects of aerobic exercise on quality of life in postmenopausal women: results from the breast Cancer and exercise trial in Alberta (BETA). Annals of Behavioral Medicine. 2016;51(3):356-64.
10.Choi H-Y, Han H-J, Choi J-W, Jung H-Y, Joa K-L. Superior Effects of High-Intensity Interval Training Compared to Conventional Therapy on Cardiovascular and Psychological Aspects in Myocardial Infarction. Annals of rehabilitation medicine. 2018;42(1):145-53.
11.Wu MH, Lee CP, Hsu SC, Chang CM, Chen CY. Effectiveness of high-intensity interval training on the mental and physical health of people with chronic schizophrenia. Neuropsychiatric disease and treatment. 2015;11:1255-63.
12.Yang X, Li F, Yang Y, Shen J, Zou R, Zhu P, et al. Efficacy and safety of echinacoside in a rat osteopenia model. Evidence-based complementary and alternative medicine : eCAM. 2013;2013:926928-.
13.Li F-H, Sun L, Zhu M, Li T, Gao H-E, Wu D-S, et al. Beneficial alterations in body composition, physical performance, oxidativestress, inflammatory markers, and adipocytokines induced by long-term high-intensity interval training in an aged rat model. Experimental gerontology. 2018;113:150-62.
14.Sanchez OA, Snow LM, Lowe DA, Serfass RC, Thompson LV. Effects of endurance exercise-training on single fiber contractile properties of insulin-treated streptozotocin-induced diabetic rats. Journal of Applied Physiology. 2005.
15.Zarrindast M-R, Farahvash H. Effects of GABA-ergic drugs on penile erection induced by apomorphine in rats. Psychopharmacology. 1994;115(1-2):249-53.
16.Zavvari F, Karimzadeh F. A Methodological Review of Development and Assessment of Behavioral Models of Depression in Rats. The Neuroscience Journal of Shefaye Khatam. 2015;3(4):151-60.
17.Earnest CP, Blair SN, Church TS. Age attenuated response to aerobic conditioning in postmenopausal women. European journal of applied physiology. 2010;110(1):75-82.
18.Bondarev D, Laakkonen EK, Finni T, Kokko K, Kujala UM, Aukee P, et al. Physical performance in relation to menopause status and physical activity. Menopause. 2018;25(12):1432-41.
19.Khammassi M, Ouerghi N, Hadj-Taieb S, Feki M, Thivel D, Bouassida A. Impact of a 12-week high-intensity interval training without caloric restriction on body composition and lipid profile in sedentary healthy overweight/obese youth. Journal of exercise rehabilitation. 2018;14(1):118-25.
20.Alahmadi M. High-intensity interval training and obesity. J Nov Physiother. 2014;4(3):211.
21.Fisher G, Brown AW, Brown MMB, Alcorn A, Noles C, Winwood L, et al. High intensity interval-vs moderate intensity-training for improving cardiometabolic health in overweight or obese males: a randomized controlled trial. PloS one. 2015;10(10):e0138853.
22.Gillen JB, Percival ME, Ludzki A, Tarnopolsky MA, Gibala MJ. Interval training in the fed or fasted state improves body composition and muscle oxidative capacity in overweight women. Obesity. 2013;21(11):2249-55.
23.Terauchi M, Hiramitsu S, Akiyoshi M, Owa Y, Kato K, Obayashi S, et al. Associations between anxiety, depression and insomnia in peri-and post-menopausal women. Maturitas. 2012;72(1):61-5.
24.Duff SM. Effect of physical activity on menopausal symptoms in non-vigorously active postmenopausal women: Citeseer; 2008.
25.McGovern M. The effects of exercise on the brain. Serendip brymawr edu. 2005.
26.Kh I, Taheri M, Seghatoleslami A. The effects of weight loss by physical activity and diet on depression levels of highly depressed elderly females. Iranian Journal of Ageing. 2015;10(1):48-53.
27.Herring MP, Lindheimer JB, O’Connor PJ. The effects of exercise training on anxiety. American Journal of Lifestyle Medicine. 2014;8(6):388-403.
Report of Health Care
Volume 5, Issue 3
July 2019
Pages 1-7

Files

Share

How to cite

Statistics